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betamethasone

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chemical compound: steroid medication

Välised allikad

MedlinePlus drug identifier
a682799
CAS Registry Number
378-44-9[1][2]
MeSH descriptor ID
D001623

teema nimetus kujul: Betamethasone

MeSH concept ID
M0002437
NSC number
39470
755911
ChEMBL ID
CHEMBL632[3]
Gran Enciclopèdia Catalana ID
betametasona
Human Metabolome Database ID
HMDB0014586[4][5]
MeSH tree code
D04.210.500.745.432.769.199
D04.210.500.908.093
AICS Chemical ID (BEING DELETED)
4305
PatientsLikeMe treatment ID
betamethasone
ECHA Substance Infocard ID
100.006.206[6]
DrugCentral ID
348[7]
NALT ID
10152
Probes And Drugs ID
PD010025
NDF-RT ID
N0000146957[1]
Freebase
/m/057fff[8]
Reaxys registry number
3176546[9]
PubChem CID
9782[10][5]
UniChem compound ID
266293[7]
Quora topic ID
Betamethasone
SPLASH
splash10-05i4-2930000000-bc11f96b96bcca3051a8
splash10-00dj-3960000000-a7dc9d06200fd3114dc2
KEGG ID
D00244[9]
OpenAlex ID
C2781162121[11]
KBpedia ID
BetamethasoneValerate[12]
InChIKey
UREBDLICKHMUKA-DVTGEIKXSA-N[10][13]
DrugBank ID
DB00443[5]
Gran Enciclopèdia Catalana ID (former scheme)
0084211
WikiProjectMed ID
Betamethasone
UNII
9842X06Q6M[1][5]
SureChEMBL ID
SCHEMBL4565[4][5]
electronic Essential Medicines List medicine ID
155
ATC code
S03BA03[14]
S01CB04[14]
R01AD06[14]
S01BA06[14]
S02BA07[14]
A07EA04[14]
D07XC01[14]
C05AA05[14]
R03BA04[14]
H02AB01[14]
D07AC01[14]
MassBank accession ID
MSBNK-Eawag-EQ324201
MSBNK-Eawag-EQ324205
MSBNK-Waters-WA001161
MSBNK-Waters-WA001162
MSBNK-Waters-WA001163
MSBNK-Waters-WA001164
MSBNK-Waters-WA001165
MSBNK-Waters-WA001166
MSBNK-Waters-WA001167
Microsoft Academic ID
2781162121
2910187197
InChI
InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1[10]
Store medisinske leksikon ID
betametason

mapping relation type: täpne vaste

DSSTOX compound identifier
DTXCID002667
UMLS CUI
C0005308[1]
Guide to Pharmacology Ligand ID
7061[15]
DSSTox substance ID
DTXSID3022667[16][5]
ChemSpider ID
9399[17]
EC number
206-825-4[1]
ChEBI ID
3077[3][18]

mapping relation type: täpne vaste

UNSPSC Code
51181701
HSDB ID
3015[19]
RxNorm ID
1514[1]

üksikjuht nähtusest

type of chemical entity

mille alamklass

(11beta)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione[20]

kasutus

ravim

keemiline struktuur

image of molecular model or crystal lattice model

kujutab: ball-and-stick model

mass/kaal

392,2 aatommassiühik[10]

stereoisomer of

dexamethasone[21]

chemical formula

C₂₂H₂₉FO₅[10]

canonical SMILES

CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C[10]

isomeric SMILES

C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C[10]

defined daily dose

0,4 milligram[22]

route of administration: nasal administration

active ingredient in

Sernivo[23]
Diprolene[24]
Luxiq[25]

World Health Organisation international non-proprietary name

betamethasone[9]

medical condition treated

scalp dermatosis[26]
pruritus ani[26]
seborrhoeic dermatitis[26]
dermatitis[26]
acropustulosis[26]
atopic dermatitis[26]
leg dermatosis[26]
facial dermatosis[26]
hand dermatosis[26]
põletik[26]
bronhiaalastma[27]

approved by: FDA

algusaeg: 17. aprill 1961

Pollinoos[27]

approved by: FDA

algusaeg: 17. aprill 1961

ulcerative colitis[27]

approved by: FDA

algusaeg: 17. aprill 1961

multiipelskleroos[27]

approved by: FDA

algusaeg: 17. aprill 1961

significant drug interaction

nabumetone[28]

side effect: gastrointestinal haemorrhage

Naprokseen[28]

side effect: gastrointestinal haemorrhage

celecoxib[28]

side effect: gastrointestinal haemorrhage

Diclofenac[28]

side effect: gastrointestinal haemorrhage

piroxicam[28]

side effect: gastrointestinal haemorrhage

meloksikaam[28]

side effect: gastrointestinal haemorrhage

(RS)-fenoprofen[28]

side effect: gastrointestinal haemorrhage

(+-)-flurbiprofen[28]

side effect: gastrointestinal haemorrhage

ibuprofeen[28]

side effect: gastrointestinal haemorrhage

Indometatsiin[28]

side effect: gastrointestinal haemorrhage

(RS)-ketoprofen[28]

side effect: gastrointestinal haemorrhage

(RS)-etodolac[28]

side effect: gastrointestinal haemorrhage

sulindac[28]

side effect: gastrointestinal haemorrhage

parecoxib[28]

side effect: gastrointestinal haemorrhage

aceclofenac[28]

side effect: gastrointestinal haemorrhage

tenoxicam[28]

side effect: gastrointestinal haemorrhage

moxifloxacin[29]

side effect: Achor-Smith syndrom

Aspiriin[30]

side effect: gastrointestinal haemorrhage

Aspiriin[30]

side effect: peptic ulcer disease

nabumetone[28]

side effect: peptic ulcer disease

Naprokseen[28]

side effect: peptic ulcer disease

celecoxib[28]

side effect: peptic ulcer disease

Diclofenac[28]

side effect: peptic ulcer disease

piroxicam[28]

side effect: peptic ulcer disease

meloksikaam[28]

side effect: peptic ulcer disease

(RS)-fenoprofen[28]

side effect: peptic ulcer disease

(+-)-flurbiprofen[28]

side effect: peptic ulcer disease

ibuprofeen[28]

side effect: peptic ulcer disease

Indometatsiin[28]

side effect: peptic ulcer disease

(RS)-ketoprofen[28]

side effect: peptic ulcer disease

(RS)-etodolac[28]

side effect: peptic ulcer disease

sulindac[28]

side effect: peptic ulcer disease

parecoxib[28]

side effect: peptic ulcer disease

aceclofenac[28]

side effect: peptic ulcer disease

tenoxicam[28]

side effect: peptic ulcer disease

Varfariin[28]

side effect: retroperitoneal hemorrhage

acenocoumarol[28]

side effect: retroperitoneal hemorrhage

moxifloxacin[29]

side effect: tendon rupture

rocuronium[28]

side effect: muscle weakness

rocuronium[28]

side effect: muscular disease

atracurium[30]

side effect: muscle weakness

atracurium[30]

side effect: muscular disease

cisatracurium[28]

side effect: muscle weakness

cisatracurium[28]

side effect: muscular disease

physically interacts with

Nuclear receptor subfamily 3 group C member 1[31]

subjektil on roll: Agonist

pregnancy category

US pregnancy category C

subjektil on roll

5-lipoxygenase inhibitor[32]
selective glucocorticoid receptor agonist[32]
anti-inflammatory agent[33]
Glükokortikosteroidid[33]
anti-asthmatic agents[33]
essential medicine

koosseisu osa

süsinik

Commonsi kategooria

Betamethasone

Viited

  1. ↑ 1,0 1,1 1,2 1,3 1,4 1,5 Global Substance Registration System, 17. november 2016, inglise keel, betamethasone, 9842X06Q6M
  2. ↑ CAS Common Chemistry, 9. aprill 2021, UREBDLICKHMUKA-DVTGEIKXSA-N, https://commonchemistry.cas.org/detail?cas_rn=378-44-9
  3. ↑ 3,0 3,1 ChEMBL, 17. november 2016, inglise keel, BETAMETHASONE, CHEMBL632
  4. ↑ 4,0 4,1 inferred from InChIKey
  5. ↑ 5,0 5,1 5,2 5,3 5,4 5,5 UREBDLICKHMUKA-DVTGEIKXSA-N, InChIKey
  6. ↑ ECHA Substance Infocard database, 27. detsember 2018, 100.006.206, Betamethasone, CAS no.: 378-44-9
  7. ↑ 7,0 7,1 UniChem
  8. ↑ Freebase Data Dumps, 28. oktoober 2013
  9. ↑ 9,0 9,1 9,2 ChEBI, 3. oktoober 2016, inglise keel, betamethasone, 3077
  10. ↑ 10,0 10,1 10,2 10,3 10,4 10,5 10,6 PubChem, 17. november 2016, inglise keel, 9782, betamethasone
  11. ↑ OpenAlex, 26. jaanuar 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
  12. ↑ KBpedia, 9. juuli 2020
  13. ↑ ChEBI release 2020-09-01
  14. ↑ 14,00 14,01 14,02 14,03 14,04 14,05 14,06 14,07 14,08 14,09 14,10 DrugBank, inglise keel, 17. november 2015, 00443, Betamethasone
  15. ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. november 2016, inglise keel, 7061, betamethasone
  16. ↑ Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard
  17. ↑ ChemSpider, 17. november 2016, inglise keel, 9399, Betamethasone
  18. ↑ International Chemical Identifier, InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
  19. ↑ Hazardous Substances Data Bank, 10. mai 2021, 28. oktoober 2019, BETAMETHASONE, 3015
  20. ↑ inferred from SMILES
  21. ↑ inferred from InChI
  22. ↑ https://www.whocc.no/atc_ddd_index/?code=R01AD06
  23. ↑ RxNorm, 1738537, 14. veebruar 2018
  24. ↑ RxNorm, 216664, 14. veebruar 2018
  25. ↑ RxNorm, 261566, 14. veebruar 2018
  26. ↑ 26,00 26,01 26,02 26,03 26,04 26,05 26,06 26,07 26,08 26,09 N0000146957, 13. detsember 2016, NDF-RT, inglise keel
  27. ↑ 27,0 27,1 27,2 27,3 Inxight: Drugs Database, 2. november 2018, https://drugs.ncats.io/drug/9842X06Q6M, http://www.accessdata.fda.gov/drugsatfda_docs/label/2015/014602s059lbl.pdf
  28. ↑ 28,00 28,01 28,02 28,03 28,04 28,05 28,06 28,07 28,08 28,09 28,10 28,11 28,12 28,13 28,14 28,15 28,16 28,17 28,18 28,19 28,20 28,21 28,22 28,23 28,24 28,25 28,26 28,27 28,28 28,29 28,30 28,31 28,32 28,33 28,34 28,35 28,36 28,37 A reference set of clinically relevant adverse drug-drug interactions, hypothetically
  29. ↑ 29,0 29,1 A reference set of clinically relevant adverse drug-drug interactions, established
  30. ↑ 30,0 30,1 30,2 30,3 A reference set of clinically relevant adverse drug-drug interactions, probably
  31. ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7061, inglise keel
  32. ↑ 32,0 32,1 N0000146957, 5. märts 2018, NDF-RT
  33. ↑ 33,0 33,1 33,2 Medical Subject Headings, 15. märts 2018, D001623
Pärit leheküljelt "https://et.wikipedia.org/wiki/Eri:AboutTopic/Q416132"