Transferrin
Ilme
mammalian protein found in Homo sapiens
osa objektist
Serotransferrin, mammalian[14]
Transferrin-like domain, protein family[15]
Transferrin family, iron binding site, protein family[15]
found in taxon
Homo sapiens[12]
encoded by
TF[12]
molecular function
cell component
biological process
Gene Atlas image
täpne vaste
Viited
- ↑ Freebase Data Dumps, 28. oktoober 2013
- ↑ 2,0 2,1 2,2 NCBI Gene, 30. mai 2020, 7018
- ↑ GF WordNet
- ↑ Ensembl Release 99, ENSP00000385834
- ↑ Ensembl Release 99, ENSP00000401505
- ↑ Ensembl Release 99, ENSP00000417468
- ↑ Ensembl Release 99, ENSP00000418396
- ↑ Ensembl Release 99, ENSP00000418716
- ↑ Ensembl Release 99, ENSP00000419338
- ↑ Ensembl Release 99, ENSP00000419714
- ↑ OpenAlex, 26. jaanuar 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
- ↑ 12,0 12,1 12,2 12,3 UniProt, 13. november 2019, P02787
- ↑ 13,00 13,01 13,02 13,03 13,04 13,05 13,06 13,07 13,08 13,09 13,10 13,11 13,12 13,13 13,14 13,15 13,16 13,17 13,18 13,19 13,20 13,21 13,22 13,23 13,24 13,25 13,26 13,27 13,28 13,29 13,30 13,31 13,32 13,33 13,34 13,35 P02787, 9. august 2016, UniProt, inglise keel
- ↑ 14,0 14,1 14,2 InterPro Release 71.0, http://www.ebi.ac.uk/interpro/protein/P02787
- ↑ 15,0 15,1 inferred from protein domain or family
- ↑ 16,0 16,1 16,2 16,3 16,4 16,5 IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, InterPro, GOA
- ↑ 17,0 17,1 17,2 17,3 IEA, 8. aprill 2019, P02787, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
- ↑ IPI, 8. aprill 2019, P02787, Transferrin receptor co-localizes and interacts with the hemochromatosis factor (HFE) and the divalent metal transporter-1 (DMT1) in trophoblast cells, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
- ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, IntAct protein interaction database, Structural basis for iron piracy by pathogenic Neisseria, GOA
- ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, IntAct protein interaction database, Mechanism for multiple ligand recognition by the human transferrin receptor, GOA
- ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, IntAct protein interaction database, Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax., GOA
- ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, IntAct protein interaction database, How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH, GOA
- ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, IntAct protein interaction database, The molecular mechanism for receptor-stimulated iron release from the plasma iron transport protein transferrin, GOA
- ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, IntAct protein interaction database, The structural basis of transferrin sequestration by transferrin-binding protein B, GOA
- ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, IntAct protein interaction database, Noncanonical interactions between serum transferrin and transferrin receptor evaluated with electrospray ionization mass spectrometry, GOA
- ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, IntAct protein interaction database, Definition of the residues required for the interaction between glycine-extended gastrin and transferrin in vitro, GOA
- ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, IntAct protein interaction database, Release of the soluble transferrin receptor is directly regulated by binding of its ligand ferritransferrin, GOA
- ↑ 28,0 28,1 IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, British Heart Foundation, HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron, GOA
- ↑ TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, British Heart Foundation, The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding, GOA
- ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, British Heart Foundation, Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor, GOA
- ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, British Heart Foundation, HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron, GOA
- ↑ 32,0 32,1 32,2 32,3 32,4 32,5 IDA, 8. aprill 2019, P02787, Transferrin receptor co-localizes and interacts with the hemochromatosis factor (HFE) and the divalent metal transporter-1 (DMT1) in trophoblast cells, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
- ↑ IDA, 8. aprill 2019, P02787, A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
- ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, British Heart Foundation, Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor, GOA
- ↑ IDA, 17. oktoober 2017, P02787, Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
- ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, Mouse Genome Informatics, Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment, GOA
- ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, Mouse Genome Informatics, Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes, GOA
- ↑ 38,00 38,01 38,02 38,03 38,04 38,05 38,06 38,07 38,08 38,09 TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, Reactome, GOA
- ↑ NAS, 8. aprill 2019, P02787, The human plasma proteome: a nonredundant list developed by combination of four separate sources, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
- ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, British Heart Foundation, Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum, GOA
- ↑ IDA, 8. aprill 2019, P02787, Rab15 effector protein: a novel protein for receptor recycling from the endocytic recycling compartment, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
- ↑ 42,0 42,1 42,2 42,3 IGI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, British Heart Foundation, HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron, GOA
- ↑ IDA, 8. aprill 2019, P02787, Truncated brush border myosin I affects membrane traffic in polarized epithelial cells, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
- ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, Community Assessment of Community Annotation with Ontologies, Ebola virus uses clathrin-mediated endocytosis as an entry pathway, GOA
- ↑ 45,0 45,1 IDA, 8. aprill 2019, P02787, Myo6 facilitates the translocation of endocytic vesicles from cell peripheries, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
- ↑ IDA, 17. oktoober 2017, P02787, Large-scale proteomics and phosphoproteomics of urinary exosomes, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
- ↑ IDA, 17. oktoober 2017, P02787, In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
- ↑ IDA, 17. oktoober 2017, P02787, Proteomic analysis of podocyte exosome-enriched fraction from normal human urine, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
- ↑ IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, 17. oktoober 2017, InterPro, GOA
- ↑ IDA, 17. oktoober 2017, P02787, Human colostrum: identification of minor proteins in the aqueous phase by proteomics, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
- ↑ IDA, 17. oktoober 2017, P02787, Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
- ↑ IDA, 17. oktoober 2017, P02787, Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
- ↑ HDA, 8. aprill 2019, P02787, Human colostrum: identification of minor proteins in the aqueous phase by proteomics, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
- ↑ HDA, 8. aprill 2019, P02787, Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
- ↑ HDA, 8. aprill 2019, P02787, Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
- ↑ HDA, 8. aprill 2019, P02787, Large-scale proteomics and phosphoproteomics of urinary exosomes, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
- ↑ HDA, 8. aprill 2019, P02787, In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
- ↑ HDA, 8. aprill 2019, P02787, Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
- ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, British Heart Foundation, Co-localization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cells, GOA
- ↑ TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, British Heart Foundation, CD81 promotes both the degradation of transferrin receptor 2 (TfR2) and the Tfr2-mediated maintenance of hepcidin expression, GOA
- ↑ IC, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, British Heart Foundation, HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron, GOA
- ↑ IEP, 17. oktoober 2017, P02787, Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
- ↑ IEA, 17. oktoober 2017, P02787, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
- ↑ HEP, 8. aprill 2019, P02787, Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
- ↑ IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8. aprill 2019, Gene Ontology Consortium, GOA
- ↑ Identifiers.org