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Glycoprotein hormones, alpha polypeptide

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mammalian protein found in Homo sapiens

Välised allikad

UMLS CUI
C0017963[1]
PDB structure ID
1DZ7[2]
1E9J[2]
1FL7[2]
1HCN[2]
1HD4[2]
1HRP[2]
1QFW[2]
1XWD[2]
4AY9[2]
4MQW[2]
Ensembl protein ID
ENSP00000486024[3]
ENSP00000358595[4]
ENSP00000482232[5]
ENSP00000486666[6]
ENSP00000487300[7]
RefSeq protein ID
NP_000726[8]
NP_001239312[8]
UniProt protein ID
P01215[9]
Microsoft Academic ID
2780181328
Freebase
/m/03d996t

üksikjuht nähtusest

valk[9]

osa objektist

Cystine-knot cytokine[10]
glycoprotein hormone alpha chain[10]

found in taxon

Homo sapiens[9]

encoded by

CGA[9]

molecular function

ravimi seotus vereplasma valkudega[11][12][13]

määramismeetod: IPI

hormone activity[14][15][16][17]

määramismeetod: IEA, IMP, TAS

hormone activity[18][19][20]

määramismeetod: IEA, IMP

follicle-stimulating hormone activity[21][22]

määramismeetod: IDA

follicle-stimulating hormone activity[23][24][25]

määramismeetod: IBA, IDA

cell component

Golgi lumen[26]

määramismeetod: TAS

extracellular region[26][19][20]

määramismeetod: IEA, TAS

extracellular space[21][22]

määramismeetod: IDA

follicle-stimulating hormone complex[21][22]

määramismeetod: IDA

extracellular space[23][24][25]

määramismeetod: IBA, IDA

follicle-stimulating hormone complex[23][24][25]

määramismeetod: IBA, IDA

biological process

cell-cell signaling[14]

määramismeetod: TAS

peptide hormone processing[26]

määramismeetod: TAS

positive regulation of cell population proliferation[27]

määramismeetod: NAS

positive regulation of transcription by RNA polymerase II[27]

määramismeetod: NAS

Signaaliülekanne[14]

määramismeetod: TAS

positive regulation of cell migration[27]

määramismeetod: NAS

regulation of transcription by RNA polymerase II[26]

määramismeetod: TAS

regulation of signaling receptor activity[28]

määramismeetod: IEA

G protein-coupled receptor signaling pathway[29]

määramismeetod: TAS

G protein-coupled receptor signaling pathway[26][24]

määramismeetod: IDA, TAS

regulation of signaling receptor activity[24]

määramismeetod: IDA

positive regulation of steroid biosynthetic process[21]

määramismeetod: IDA

thyroid hormone generation[25]

määramismeetod: IBA

positive regulation of steroid biosynthetic process[23][25]

määramismeetod: IBA, IDA

Viited

  1. ↑ UMLS 2023, 24. mai 2023, inferred by common MeSH mappings on source and on Wikidata
  2. ↑ 2,00 2,01 2,02 2,03 2,04 2,05 2,06 2,07 2,08 2,09 P01215, 9. august 2016, UniProt, inglise keel
  3. ↑ Ensembl Release 99, ENSP00000486024
  4. ↑ Ensembl Release 99, ENSP00000358595
  5. ↑ Ensembl Release 99, ENSP00000482232
  6. ↑ Ensembl Release 99, ENSP00000486666
  7. ↑ Ensembl Release 99, ENSP00000487300
  8. ↑ 8,0 8,1 NCBI Gene, 30. mai 2020, 1081
  9. ↑ 9,0 9,1 9,2 9,3 UniProt, 13. november 2019, P01215
  10. ↑ 10,0 10,1 InterPro Release 71.0, http://www.ebi.ac.uk/interpro/protein/P01215
  11. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, 8. aprill 2019, IntAct protein interaction database, Structure of human follicle-stimulating hormone in complex with its receptor, GOA
  12. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, 8. aprill 2019, IntAct protein interaction database, Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor, GOA
  13. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, 8. aprill 2019, IntAct protein interaction database, Three-dimensional structure of human follicle-stimulating hormone, GOA
  14. ↑ 14,0 14,1 14,2 TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01215&geneProductId=UniProtKB:P01215, 31. oktoober 2017, Proteome Inc., Isolation, cloning and sequence analysis of the cDNA for the α-subunit of human chorionic gonadotropin, GOA
  15. ↑ IMP, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01215&geneProductId=UniProtKB:P01215, 31. oktoober 2017, AgBase, Molecular biology of channel catfish gonadotropin receptors: 1. Cloning of a functional luteinizing hormone receptor and preovulatory induction of gene expression, GOA
  16. ↑ IEA, 31. oktoober 2017, P01215, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01215&geneProductId=UniProtKB:P01215, UniProt
  17. ↑ IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01215&geneProductId=UniProtKB:P01215, 31. oktoober 2017, InterPro, GOA
  18. ↑ IMP, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, 8. aprill 2019, AgBase, Molecular biology of channel catfish gonadotropin receptors: 1. Cloning of a functional luteinizing hormone receptor and preovulatory induction of gene expression, GOA
  19. ↑ 19,0 19,1 IEA, 8. aprill 2019, P01215, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, UniProt
  20. ↑ 20,0 20,1 IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, 8. aprill 2019, InterPro, GOA
  21. ↑ 21,0 21,1 21,2 21,3 IDA, 1. jaanuar 2018, P01215, Expression of biologically active human follitropin in Chinese hamster ovary cells, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, UniProt
  22. ↑ 22,0 22,1 22,2 IDA, 1. jaanuar 2018, P01215, Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, UniProt
  23. ↑ 23,0 23,1 23,2 23,3 IDA, 8. aprill 2019, P01215, Expression of biologically active human follitropin in Chinese hamster ovary cells, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, UniProt
  24. ↑ 24,0 24,1 24,2 24,3 24,4 IDA, 8. aprill 2019, P01215, Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, UniProt
  25. ↑ 25,0 25,1 25,2 25,3 25,4 IBA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, 8. aprill 2019, GO Central, Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium, GOA
  26. ↑ 26,0 26,1 26,2 26,3 26,4 TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, 8. aprill 2019, Reactome, GOA
  27. ↑ 27,0 27,1 27,2 NAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, 8. aprill 2019, British Heart Foundation, Follicular stimulating hormone enhances Notch 1 expression in SK-OV-3 ovarian cancer cells, GOA
  28. ↑ IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01215&geneProductId=UniProtKB:P01215, 31. oktoober 2017, Gene Ontology Consortium, GOA
  29. ↑ TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01215&geneProductId=UniProtKB:P01215, 31. oktoober 2017, Reactome, GOA
Pärit leheküljelt "https://et.wikipedia.org/wiki/Eri:AboutTopic/Q21108609"