Transkraniaalne magnetstimulatsioon

Transkraniaalne magnetstimulatsioon (TMS) on meetod, mille käigus tekitatakse poolis elektrivoolu abil magnetväli, mis ajule piisavalt lähedal olles mõjutab neuronite elektrilist talitlust. Baltikumis esmakordselt hakati seda meetodit teadusuurimustes kasutama Eestis. Eesti Käitumis- ja Terviseteaduste Tippkeskuse taju ja teadvuse uurimisrühm (juhendaja Talis Bachmann) on vastaval teemal avaldanud rea uurimistöid rahvusvahelistes eelretsenseeritavates teadusajakirjades ja konverentsiteesides.^[1]

↑ Murd, C., Aru, J., Hiio, M., Luiga, I., & Bachmann, T. (2010). Caffeine enhances frontal relative negativity of slow brain potentials in a task-free experimental setup. Brain Research Bulletin, 82(1-2), 39-45. Murd, C., Luiga, I., Kreegipuu, K., & Bachmann, T. (2010). Scotomas induced by multiple, spatially invariant TMS pulses have stable size and subjective contrast. International Journal of Psychophysiology, 77(2), 157-165. Stamm, M., Aru, J., Bachmann, T. (2011). Right-frontal slow negative potentials evoked by occipital TMS are reduced in NREM sleep. Neuroscience Letters, 493(3), 116-121. Karton, I., & Bachmann, T. (2011). Effect of prefrontal transcranial magnetic stimulation on spontaneous truth-telling. Behavioural Brain Research, 225(1), 209-214. Aru, J., Korjus, K., Murd, C., & Bachmann, T. (2012). Spectral signatures of the effects of caffeine and occipitally applied transcranial magnetic stimulation in a task-free experimental setup. Journal of Caffeine Research, 2(1), 23-30. Murd, C., Einberg, A., & Bachmann, T. (2012). Repetitive TMS over V5/MT shortens the duration of spatially localized motion aftereffect: The effects of pulse intensity and stimulation hemisphere. Vision Research, 68, 59–64. Rutiku, R., Einberg, A., Imanaka, K., & Bachmann, T. (2013). P 143. The contents of a steady visual background have an effect on TMS-evoked EEG perturbation: Natural scenes compared to scenes with man-made environments increase ERP slow negativity. Clinical Neurophysiology, 124(10), e131-e132. doi:10.1016/j.clinph.2013.04.220 Rutiku, R., Peterson, K., & Bachmann, T. (2013). P 149. DLPFC is involved in perceptual decision-making but not metacognitive evaluation. Clinical Neurophysiology, 124(10), e134-e135. doi:10.1016/j.clinph.2013.04.226 Rutiku, R., Einberg, A., Imanaka, K., & Bachmann, T. (2013). The effect of task-irrelevant visual backgrounds on human transcranial magnetic stimulation-evoked electroencephalography responses and cortical alpha activity. European Journal of Neuroscience, 38(12), 3768-3777. Karton, I., Rinne, J.-M., & Bachmann, T. (2014). Facilitating the right but not left DLPFC by TMS decreases truthfulness of object-naming responses. Behavioural Brain Research, 271, 89-93. Karton, I., Palu, A., Jõks, K., & Bachmann, T. (2014). Deception rate in a “lying game”: Different effects of excitatory repetitive transcranial magnetic stimulation of right and left dorsolateral prefrontal cortex not found with inhibitory stimulation. Neuroscience Letters, 583, 21-25. Stamm, M., Aru, J., Rutiku, R., & Bachmann, T. (2015). Long-interval paired pulse TMS leads to late positive wave components in NREM sleep. Brain Stimulation, 8 (Abstracts, 263), 392. Rutiku, R., Tulver, K., Aru, J., & Bachmann, T. (2015). Frontally applied pre-stimulus TMS decreases discrimination performance. Brain Stimulation, 8 (Abstracts, 264), 392. Stamm, M., Aru, J., Rutiku, R., & Bachmann, T. (2015). Occipital long-interval paired pulse TMS leads to slow wave components in NREM sleep. Consciousness and Cognition, 35(5), 78-87. Bachmann, T., & Rutiku, R. (2015). TMS and consciousness: a view from the University of Tartu in Tallinn. Toward a Science of Consciousness 2015, Proceedings of the 21^st annual international conference (p. 119), Helsinki: Hakapaino OY. Aru, J., Stamm, M., Rutiku, R., & Bachmann, T. (2015). TMS to occipital cortex in the awake state and NREM sleep. Toward a Science of Consciousness 2015, Proceedings of the 21^st annual international conference (p. 120), Helsinki: Hakapaino OY. Rutiku, R., Tulver, K., Aru, J., & Bachmann, T. (2016). Visual masking with frontally applied pre-stimulus TMS and its subject-specific neural correlates. Brain Research, 1642, 136-145. Tulviste, J., Goldberg, E., Podell, K., & Bachmann, T. (2016). Effects of repetitive transcranial magnetic stimulation on non-veridical decision making. Acta Neurobiologiae Experimentalis, 76(3), 182–191. Karton, I., & Bachmann, T. (2017). Disrupting dorsolateral prefrontal cortex by rTMS reduces the P300 based marker of deception. Brain and Behavior, 7(4), 1-8. DOI: 10.1002/brb3.656 Bachmann, T. (2018). On a strategy of advancement of TMS based methods for studying NCC. Frontiers in Psychology, 9, 2026 (2018). Tulviste, J., & Bachmann, T. (2019). Diminished Risk-Aversion After Right DLPFC Stimulation: Effects of rTMS on a Risky Ball Throwing Task. Journal of the International Neuropsychological Society, 25(1), 72-78. doi:10.1017/S1355617718000930 Tulviste, J., Goldberg, E., Podell, K., Vaht, M., Harro, J., & Bachmann, T. (2019). BDNF polymorphism in non-veridical decision making and differential effects of rTMS. Behavioural Brain Research, 364, 177-182.

[1] Murd, C., Aru, J., Hiio, M., Luiga, I., & Bachmann, T. (2010). Caffeine enhances frontal relative negativity of slow brain potentials in a task-free experimental setup. Brain Research Bulletin, 82(1-2), 39-45. Murd, C., Luiga, I., Kreegipuu, K., & Bachmann, T. (2010). Scotomas induced by multiple, spatially invariant TMS pulses have stable size and subjective contrast. International Journal of Psychophysiology, 77(2), 157-165. Stamm, M., Aru, J., Bachmann, T. (2011). Right-frontal slow negative potentials evoked by occipital TMS are reduced in NREM sleep. Neuroscience Letters, 493(3), 116-121. Karton, I., & Bachmann, T. (2011). Effect of prefrontal transcranial magnetic stimulation on spontaneous truth-telling. Behavioural Brain Research, 225(1), 209-214. Aru, J., Korjus, K., Murd, C., & Bachmann, T. (2012). Spectral signatures of the effects of caffeine and occipitally applied transcranial magnetic stimulation in a task-free experimental setup. Journal of Caffeine Research, 2(1), 23-30. Murd, C., Einberg, A., & Bachmann, T. (2012). Repetitive TMS over V5/MT shortens the duration of spatially localized motion aftereffect: The effects of pulse intensity and stimulation hemisphere. Vision Research, 68, 59–64. Rutiku, R., Einberg, A., Imanaka, K., & Bachmann, T. (2013). P 143. The contents of a steady visual background have an effect on TMS-evoked EEG perturbation: Natural scenes compared to scenes with man-made environments increase ERP slow negativity. Clinical Neurophysiology, 124(10), e131-e132. doi:10.1016/j.clinph.2013.04.220 Rutiku, R., Peterson, K., & Bachmann, T. (2013). P 149. DLPFC is involved in perceptual decision-making but not metacognitive evaluation. Clinical Neurophysiology, 124(10), e134-e135. doi:10.1016/j.clinph.2013.04.226 Rutiku, R., Einberg, A., Imanaka, K., & Bachmann, T. (2013). The effect of task-irrelevant visual backgrounds on human transcranial magnetic stimulation-evoked electroencephalography responses and cortical alpha activity. European Journal of Neuroscience, 38(12), 3768-3777. Karton, I., Rinne, J.-M., & Bachmann, T. (2014). Facilitating the right but not left DLPFC by TMS decreases truthfulness of object-naming responses. Behavioural Brain Research, 271, 89-93. Karton, I., Palu, A., Jõks, K., & Bachmann, T. (2014). Deception rate in a “lying game”: Different effects of excitatory repetitive transcranial magnetic stimulation of right and left dorsolateral prefrontal cortex not found with inhibitory stimulation. Neuroscience Letters, 583, 21-25. Stamm, M., Aru, J., Rutiku, R., & Bachmann, T. (2015). Long-interval paired pulse TMS leads to late positive wave components in NREM sleep. Brain Stimulation, 8 (Abstracts, 263), 392. Rutiku, R., Tulver, K., Aru, J., & Bachmann, T. (2015). Frontally applied pre-stimulus TMS decreases discrimination performance. Brain Stimulation, 8 (Abstracts, 264), 392. Stamm, M., Aru, J., Rutiku, R., & Bachmann, T. (2015). Occipital long-interval paired pulse TMS leads to slow wave components in NREM sleep. Consciousness and Cognition, 35(5), 78-87. Bachmann, T., & Rutiku, R. (2015). TMS and consciousness: a view from the University of Tartu in Tallinn. Toward a Science of Consciousness 2015, Proceedings of the 21^st annual international conference (p. 119), Helsinki: Hakapaino OY. Aru, J., Stamm, M., Rutiku, R., & Bachmann, T. (2015). TMS to occipital cortex in the awake state and NREM sleep. Toward a Science of Consciousness 2015, Proceedings of the 21^st annual international conference (p. 120), Helsinki: Hakapaino OY. Rutiku, R., Tulver, K., Aru, J., & Bachmann, T. (2016). Visual masking with frontally applied pre-stimulus TMS and its subject-specific neural correlates. Brain Research, 1642, 136-145. Tulviste, J., Goldberg, E., Podell, K., & Bachmann, T. (2016). Effects of repetitive transcranial magnetic stimulation on non-veridical decision making. Acta Neurobiologiae Experimentalis, 76(3), 182–191. Karton, I., & Bachmann, T. (2017). Disrupting dorsolateral prefrontal cortex by rTMS reduces the P300 based marker of deception. Brain and Behavior, 7(4), 1-8. DOI: 10.1002/brb3.656 Bachmann, T. (2018). On a strategy of advancement of TMS based methods for studying NCC. Frontiers in Psychology, 9, 2026 (2018). Tulviste, J., & Bachmann, T. (2019). Diminished Risk-Aversion After Right DLPFC Stimulation: Effects of rTMS on a Risky Ball Throwing Task. Journal of the International Neuropsychological Society, 25(1), 72-78. doi:10.1017/S1355617718000930 Tulviste, J., Goldberg, E., Podell, K., Vaht, M., Harro, J., & Bachmann, T. (2019). BDNF polymorphism in non-veridical decision making and differential effects of rTMS. Behavioural Brain Research, 364, 177-182.

[1]