loratadine
chemical compound; medication used to treat allergies
üksikjuht nähtusest
type of chemical entity
mille alamklass
kasutus
keemiline struktuur
mass/kaal
382,144806 aatommassiühik[22]
chemical formula
C₂₂H₂₃ClN₂O₂[3]
canonical SMILES
CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1[3]
defined daily dose
5 milligram
route of administration: oral administration
active ingredient in
Loradamed[24]
Alavert[25]
Qlearquil Allergy Relief[26]
Claritin[27]
Clear-Atadine[28]
Tavist Non-Sedating[29]
Wal-itin[30]
Cleartime Indoor & Outdoor Allergies[31]
World Health Organisation international non-proprietary name
loratadine[8]
found in taxon
Penicillium granulatum[32]
medical condition treated
seasonal allergic rhinitis[34]
paranasal sinus disease[34]
nasopharyngitis[34]
sinusitis[34]
physically interacts with
legal status (medicine)
boxed warning[36]
pregnancy category
Australian pregnancy category B1
US pregnancy category B
LiverTox likelihood score
LiverTox toxicity likelihood category E*[37]
subjektil on roll
H1 antagonist[38]
anti-allergic agents[39]
non-sedating histamine H1 antagonist[39]
antipruritic[39]
essential medicine
Commonsi kategooria
Loratadine
Viited
- ↑ 1,0 1,1 1,2 1,3 1,4 Global Substance Registration System, 19. november 2016, inglise keel, loratadine, 7AJO3BO7QN
- ↑ CAS Common Chemistry, 7. aprill 2021, https://commonchemistry.cas.org/detail?cas_rn=79794-75-5, JCCNYMKQOSZNPW-UHFFFAOYSA-N
- ↑ 3,0 3,1 3,2 3,3 3,4 PubChem, 19. november 2016, inglise keel, 3957, 79794-75-5
- ↑ 4,0 4,1 4,2 4,3 4,4 4,5 JCCNYMKQOSZNPW-UHFFFAOYSA-N, InChIKey
- ↑ 5,0 5,1 UniChem
- ↑ Quora
- ↑ DrugBank, inglise keel, 17. november 2015, 00455, Loratadine
- ↑ 8,0 8,1 ChEMBL, 19. jaanuar 2016, inglise keel, Loratadine, CHEMBL998
- ↑ Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard
- ↑ OpenAlex, 26. jaanuar 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
- ↑ ChEMBL, 19. november 2016, inglise keel, LORATADINE, CHEMBL998
- ↑ KBpedia, 9. juuli 2020
- ↑ ChEBI release 2020-09-01
- ↑ ChEBI release 2019-10-02
- ↑ International Chemical Identifier, InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3
- ↑ 16,0 16,1 inferred from InChIKey
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 19. november 2016, inglise keel, 7216, loratadine
- ↑ http://echa.europa.eu/de/information-on-chemicals/registered-substances
- ↑ ChemSpider, 19. november 2016, inglise keel, 3820, Loratadine
- ↑ ECHA Substance Infocard database, 27. detsember 2018, 100.120.122, ethyl 4-{13-chloro-4-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene}piperidine-1-carboxylate, CAS no.: 79794-75-5
- ↑ Hazardous Substances Data Bank, 10. mai 2021, 28. oktoober 2019, LORATADINE, 3578
- ↑ PubChem, 3. oktoober 2016, inglise keel, 3957, 79794-75-5
- ↑ https://www.whocc.no/atc_ddd_index/?code=R06AX13
- ↑ RxNorm, 1020123, 14. veebruar 2018
- ↑ RxNorm, 352401, 14. veebruar 2018
- ↑ RxNorm, 1534651, 14. veebruar 2018
- ↑ RxNorm, 203576, 14. veebruar 2018
- ↑ RxNorm, 602182, 14. veebruar 2018
- ↑ RxNorm, 405348, 14. veebruar 2018
- ↑ RxNorm, 700794, 14. veebruar 2018
- ↑ RxNorm, 1650989, 14. veebruar 2018
- ↑ Spirograterpene A, a Tetracyclic Spiro-Diterpene with a Fused 5/5/5/5 Ring System from the Deep-Sea-Derived Fungus Penicillium granulatum MCCC 3A00475.
- ↑ N0000148306, 13. detsember 2016, NDF-RT, inglise keel
- ↑ 34,0 34,1 34,2 34,3 34,4 Drug Indications Extracted from FAERS, 2. oktoober 2018
- ↑ 35,0 35,1 IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7216, inglise keel
- ↑ FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links., https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
- ↑ LiverTox, 8. aprill 2021, https://www.ncbi.nlm.nih.gov/books/n/livertox/LoratadineDesloratad, 16. jaanuar 2017
- ↑ N0000148306, 5. märts 2018, NDF-RT
- ↑ 39,0 39,1 39,2 Medical Subject Headings, 15. märts 2018, D017336